Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | RAD52 | P43351 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | EGFR | P00533 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | FGB | P02675 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20473193 | 0.89 | TOP2B (0.56) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL31218593 | 0.89 | MAPT (0.71) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL3420790 | 0.87 | SMN1; SMN2 (0.64) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL3853558 | 0.86 | TERT (0.63) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL20334281 | 0.81 | SMN1; SMN2 (0.55) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL31218585 | 0.81 | MAPT (0.63) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL3418752 | 0.81 | MAPT (0.63) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL13434544 | 0.80 | SMN1; SMN2 (0.59) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL18984755 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 | |
| SCHEMBL30818304 | 0.79 | SMN1; SMN2 (0.67) | SMN1; SMN2MAPTMAPK1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110536704-B | Tissue targeting complexes | 帕瑞姆普公司 | 2022-09-27 | — | — | CN | disclosed |