Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.63 |
| ▸ | EGFR | P00533 | 3/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | RAD52 | P43351 | 3/20 | 0.63 |
| ▸ | BLM | P54132 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.63 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 3/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31218585 | 1.00 | MAPT (0.63) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3418821 | 0.95 | TERT (0.61) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3416154 | 0.94 | TERT (0.62) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL31218593 | 0.91 | MAPT (0.71) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL13434540 | 0.91 | TERT (0.57) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL14882640 | 0.90 | TERT (0.56) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL7557626 | 0.89 | MALT1 (0.62) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL31218590 | 0.89 | MALT1 (0.62) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL29587040 | 0.89 | MALT1 (0.62) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL3415549 | 0.88 | NSD2 (0.62) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100062429-A1 | Fluorochromes for organelle tracing and multi-color imaging | ENZO LIFE SCIENCES, INC. | 2010-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100062429-A1 | Fluorochromes for organelle tracing and multi-color imaging | MFN2, TFEB, NDC1 | MAPT 469/4885SMN1; SMN2 2076/4885MEN1 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.