Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844979 | 0.85 | IRAK4 (0.52) | GAAKMT2AMEN1NPSR1HSD17B10 | |
| SCHEMBL29684819 | 0.81 | TSHR (0.76) | KMT2AMEN1NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL29732943 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL28844881 | 0.80 | KMT2A (0.54) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL29733013 | 0.79 | MEN1 (0.57) | KMT2AMEN1HSD17B10ALDH1A1MAPT | |
| SCHEMBL28844878 | 0.79 | MEN1 (0.57) | KMT2AMEN1HSD17B10ALDH1A1MAPT | |
| SCHEMBL29684162 | 0.77 | IRAK4 (0.50) | KMT2AMEN1NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL28844977 | 0.77 | KMT2A (0.53) | KMT2AMEN1NPSR1NPC1RAB9A | |
| SCHEMBL28844848 | 0.77 | HTT (0.70) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL29732956 | 0.77 | HTT (0.70) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |