Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28844978 | 0.85 | GAA (0.60) | IRAK4KMT2AHSD17B10TSHRKDM4E | |
| SCHEMBL29684819 | 0.80 | TSHR (0.76) | KMT2AHSD17B10TSHRKDM4EPOLB | |
| SCHEMBL29684338 | 0.78 | IRAK4 (0.49) | IRAK4KMT2AHSD17B10KDM4EPOLB | |
| SCHEMBL29732943 | 0.76 | KMT2A (0.54) | IRAK4KMT2AKDM4EPOLBHTT | |
| SCHEMBL29684162 | 0.76 | IRAK4 (0.50) | IRAK4KMT2AHSD17B10KDM4EHTT | |
| SCHEMBL28844881 | 0.76 | KMT2A (0.54) | IRAK4KMT2AKDM4EPOLBHTT | |
| SCHEMBL28844977 | 0.76 | KMT2A (0.53) | IRAK4KMT2AKDM4EPOLBHTT | |
| SCHEMBL29732956 | 0.76 | HTT (0.70) | IRAK4KMT2AKDM4EPOLBHTT | |
| SCHEMBL28844848 | 0.76 | HTT (0.70) | IRAK4KMT2AKDM4EPOLBHTT | |
| SCHEMBL29733013 | 0.75 | MEN1 (0.57) | IRAK4KMT2AHSD17B10KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | claimed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | claimed |
| CN-114763347-B | Compound for inducing mesenchymal stem cells to differentiate into cartilage and application thereof | 华东师范大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-114763347-A | Compound for inducing mesenchymal stem cells to differentiate towards cartilage and application thereof | 华东师范大学 | 2022-07-19 | — | — | CN | disclosed |