Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.65 |
| ▸ | CA9 | Q16790 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335164 | 0.84 | ALDH1A1 (0.50) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL15842273 | 0.82 | CA12 (0.75) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL11901558 | 0.79 | MAPT (0.57) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL30933370 | 0.79 | CA12 (1.00) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL3527681 | 0.79 | CA12 (1.00) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL1800595 | 0.78 | CA1 (0.56) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL11376231 | 0.78 | CA12 (0.83) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL2154447 | 0.78 | CA12 (0.69) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL19484976 | 0.77 | CYP1B1 (0.60) | CA12CA9MAPTALDH1A1KDM4E | |
| SCHEMBL28143419 | 0.77 | KDM4E (0.56) | CA12CA9MAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115057840-B | Synthesis method of 3-acyl coumarin compound promoted by visible light | 湖南理工学院 | 2023-09-26 | — | — | CN | disclosed |
| CN-115057840-A | Synthesis method of 3-acylcoumarin compound promoted by visible light | 湖南理工学院 | 2022-09-16 | — | — | CN | disclosed |