Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.69 |
| ▸ | CA9 | Q16790 | 6/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | VKORC1 | Q9BQB6 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15842273 | 0.84 | CA12 (0.75) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30933370 | 0.81 | CA12 (1.00) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3527681 | 0.81 | CA12 (1.00) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24358817 | 0.79 | CA12 (0.67) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL24199378 | 0.78 | CA12 (0.66) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6578099 | 0.78 | CA12 (0.65) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28844992 | 0.78 | CA12 (0.65) | CA12CA9HSD17B10KDM4EALDH1A1 | |
| SCHEMBL18702897 | 0.77 | CA12 (0.47) | CA12CA9HSD17B10KDM4EALDH1A1 | |
| SCHEMBL13315777 | 0.76 | CA12 (0.63) | CA12CA9KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL5472418 | 0.76 | HSD17B10 (0.54) | CA12CA9HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927727-B2 | Thiol detection | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| EP-2574193-A2 | THIOL DETECTION | Strongin, Robert, M. (US) | 2013-04-03 | — | — | EP | disclosed |
| US-20120276649-A1 | THIOL DETECTION | THE OREGON BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY | 2012-11-01 | — | — | US | disclosed |
| WO-2011082354-A2 | THIOL DETECTION | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120276649-A1 | THIOL DETECTION | GLO1, AHCY, BHMT2 | CA12 292/4885CA9 921/4885HSD17B10 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.