Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28151098 | 0.90 | GLA (0.33) | HTR6GLAGAAMAPTALK | |
| SCHEMBL27518193 | 0.74 | RPS6KA3 (0.31) | GAAMAPT | |
| SCHEMBL28195323 | 0.71 | BRD4 (0.40) | — | |
| SCHEMBL17315403 | 0.70 | KIF11 (0.54) | MAPT | |
| SCHEMBL28152167 | 0.70 | TAAR1 (0.41) | GAAMAPT | |
| SCHEMBL27468059 | 0.69 | — | — | |
| SCHEMBL27328290 | 0.67 | ALOX5 (0.43) | MAPT | |
| SCHEMBL25691830 | 0.63 | MCHR1 (0.47) | MAPT | |
| SCHEMBL12432958 | 0.63 | APP (0.44) | GLAGAAMAPT | |
| SCHEMBL28626908 | 0.62 | TYR (0.41) | HTR6GLAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106794181-A | MTH1 inhibitors for the treatment of inflammatory and autoimmune conditions | 托马斯·黑勒戴药物研究基金会 | 2017-05-31 | — | — | CN | disclosed |