Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 2/20 | 0.55 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 4/20 | 0.55 |
| ▸ | DNMT3A | Q9Y6K1 | 4/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | GAK | O14976 | 2/20 | 0.47 |
| ▸ | DNMT3L | Q9UJW3 | 3/20 | 0.47 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.46 |
| ▸ | STK3 | Q13188 | 1/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845668 | 0.89 | GAA (0.60) | DNMT1DNMT3AAURKAGAKDNMT3L | |
| SCHEMBL28845675 | 0.88 | DNMT1 (0.68) | KCNK3DNMT1DNMT3AAURKAGAK | |
| SCHEMBL28845637 | 0.86 | DNMT1 (0.52) | DNMT1DNMT3AAURKAGAKDNMT3L | |
| SCHEMBL28845687 | 0.84 | ALDH1A1 (0.57) | DNMT1DNMT3AAURKAGAKDNMT3L | |
| SCHEMBL28845693 | 0.84 | MEN1 (0.61) | KCNK3KCNK9DNMT1DNMT3AAURKA | |
| SCHEMBL29809955 | 0.84 | MEN1 (0.61) | KCNK3KCNK9DNMT1DNMT3AAURKA | |
| SCHEMBL29200469 | 0.82 | GAK (0.55) | DNMT1DNMT3AAURKAGAKGSK3A | |
| SCHEMBL28845688 | 0.82 | DNMT1 (0.63) | DNMT1DNMT3AAURKAGAKDNMT3L | |
| SCHEMBL28845648 | 0.82 | NPSR1 (0.56) | DNMT1DNMT3AAURKAGAKDNMT3L | |
| SCHEMBL28845651 | 0.81 | GPR52 (0.54) | DNMT1DNMT3AGAKGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |