Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | GAK | O14976 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28845629 | 0.91 | MAPKAPK2 (0.49) | MAPTALDH1A1GAAALOX15HTT | |
| SCHEMBL30771663 | 0.91 | MAPKAPK2 (0.49) | MAPTALDH1A1MAPK1HTTLMNA | |
| SCHEMBL29200486 | 0.91 | MAPKAPK2 (0.49) | MAPTALDH1A1MAPK1HTTLMNA | |
| SCHEMBL28845661 | 0.91 | SCN9A (0.48) | MAPTGAAHTTLMNAGPR52 | |
| SCHEMBL28845640 | 0.90 | MAPKAPK2 (0.49) | GPR52MAPKAPK2GAKKMT2ADRD2 | |
| SCHEMBL28845636 | 0.89 | DRD2 (0.51) | MAPTGAAMAPK1HTTTDP1 | |
| SCHEMBL28845652 | 0.88 | RAD52 (0.49) | MAPTALDH1A1MAPK1HTTLMNA | |
| SCHEMBL29809902 | 0.86 | ABL1 (0.50) | MAPTGPR52MAPKAPK2KMT2ASCN9A | |
| SCHEMBL28845642 | 0.86 | ABL1 (0.50) | MAPTGPR52MAPKAPK2KMT2ASCN9A | |
| SCHEMBL29809938 | 0.83 | HPGD (0.56) | ALDH1A1LMNAGPR52MAPKAPK2GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |