Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | BCR | P11274 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809902 | 1.00 | ABL1 (0.50) | ABL1BCRKMT2AMEN1POLB | |
| SCHEMBL28845640 | 0.93 | MAPKAPK2 (0.49) | ABL1BCRKMT2AMEN1POLB | |
| SCHEMBL28845636 | 0.92 | DRD2 (0.51) | ABL1BCRKMT2AMEN1POLB | |
| SCHEMBL29200486 | 0.91 | MAPKAPK2 (0.49) | ABL1BCRKMT2AMEN1POLB | |
| SCHEMBL30771663 | 0.91 | MAPKAPK2 (0.49) | ABL1BCRKMT2AMEN1POLB | |
| SCHEMBL28845652 | 0.88 | RAD52 (0.49) | KMT2AMEN1POLBSMN1; SMN2GPR52 | |
| SCHEMBL28845689 | 0.86 | MAPT (0.52) | KMT2AGPR52SCN9AMAPKAPK2MAPT | |
| SCHEMBL29809901 | 0.86 | KMT2A (0.52) | KMT2AMEN1POLBSMN1; SMN2PHGDH | |
| SCHEMBL28845644 | 0.86 | KMT2A (0.52) | KMT2AMEN1POLBSMN1; SMN2PHGDH | |
| SCHEMBL29809938 | 0.86 | HPGD (0.56) | ABL1BCRKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | claimed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | claimed |
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |