Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.49 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 2/20 | 0.46 |
| ▸ | BCR | P11274 | 2/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30771663 | 1.00 | MAPKAPK2 (0.49) | MAPKAPK2GPR52SCN9APOLBSMN1; SMN2 | |
| SCHEMBL28845636 | 0.96 | DRD2 (0.51) | MAPKAPK2GPR52POLBSMN1; SMN2MEN1 | |
| SCHEMBL28845640 | 0.95 | MAPKAPK2 (0.49) | MAPKAPK2GPR52SCN9APOLBSMN1; SMN2 | |
| SCHEMBL28845652 | 0.95 | RAD52 (0.49) | MAPKAPK2GPR52POLBSMN1; SMN2MEN1 | |
| SCHEMBL28845661 | 0.93 | SCN9A (0.48) | MAPKAPK2GPR52SCN9APOLBSMN1; SMN2 | |
| SCHEMBL28845642 | 0.91 | ABL1 (0.50) | MAPKAPK2GPR52SCN9APOLBSMN1; SMN2 | |
| SCHEMBL29809902 | 0.91 | ABL1 (0.50) | MAPKAPK2GPR52SCN9APOLBSMN1; SMN2 | |
| SCHEMBL28845689 | 0.91 | MAPT (0.52) | MAPKAPK2GPR52SCN9AKMT2ADRD2 | |
| SCHEMBL29809938 | 0.89 | HPGD (0.56) | MAPKAPK2GPR52POLBMEN1KMT2A | |
| SCHEMBL29809947 | 0.87 | ADRB2 (0.49) | MAPKAPK2GPR52POLBEPHX2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |