Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | GSK3A | P49840 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 4/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.48 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.48 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.48 |
| ▸ | MARK3 | P27448 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.48 |
| ▸ | STK3 | Q13188 | 1/20 | 0.48 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.48 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809960 | 1.00 | MAPT (0.51) | MAPTKDM4ETP53GAAGSK3A | |
| SCHEMBL28845694 | 0.86 | TP53 (0.52) | MAPTKDM4ETP53GAAGSK3A | |
| SCHEMBL29809952 | 0.86 | TP53 (0.52) | MAPTKDM4ETP53GAAGSK3A | |
| SCHEMBL28845642 | 0.84 | ABL1 (0.50) | MAPTMAPKAPK2RAB9AKMT2APHGDH | |
| SCHEMBL29809902 | 0.84 | ABL1 (0.50) | MAPTMAPKAPK2RAB9AKMT2APHGDH | |
| SCHEMBL29809955 | 0.80 | MEN1 (0.61) | MAPTGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845693 | 0.80 | MEN1 (0.61) | MAPTGSK3AGSK3BCLK4KDR | |
| SCHEMBL28845640 | 0.77 | MAPKAPK2 (0.49) | MAPKAPK2KMT2APHGDHABL1MEN1 | |
| SCHEMBL28845668 | 0.76 | GAA (0.60) | MAPTGAAGSK3AGSK3BCLK4 | |
| SCHEMBL28845644 | 0.76 | KMT2A (0.52) | MAPTMAPKAPK2KMT2APHGDHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773267-B | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2024-01-26 | — | — | CN | disclosed |
| CN-114773267-A | [ (7-trifluoromethyl quinoline-4-yl) amino ] benzamide compound and preparation and application thereof | 沈阳药科大学 | 2022-07-22 | — | — | CN | disclosed |