Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 4/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28520565 | 1.00 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL29007627 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL28583241 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL10707607 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL9421516 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL9421519 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL1643304 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL3111958 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| Hydrochloric Acid SCHEMBL6494113 | 0.93 | ALDH1A1 (0.35) | ALDH1A1HIF1ANOTUMTSHRTDP1 | |
| SCHEMBL5028626 | 0.89 | ALDH1A1 (0.38) | ALDH1A1HIF1ATSHRTDP1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114773511-A | Mannose-containing polymer and preparation method thereof | 上海应用技术大学 | 2022-07-22 | — | — | CN | claimed |
| CN-112830905-B | Benzo [ f ] indeno [1,2-d ] [1,2] thiazepine 5-oxy series compounds having a quaternary ring system structure | 江西师范大学 | 2023-04-14 | — | — | CN | disclosed |
| CN-114773511-A | Mannose-containing polymer and preparation method thereof | 上海应用技术大学 | 2022-07-22 | — | — | CN | disclosed |