Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TSHR | P16473 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30671937 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| SCHEMBL29557118 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| SCHEMBL29445548 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| SCHEMBL29639024 | 0.92 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL6494113 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL9421519 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL28520565 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL1643304 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL9421516 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1ALOX12CA1 | |
| Hydrochloric Acid SCHEMBL29007627 | 0.89 | ALDH1A1 (0.35) | ALDH1A1TSHRTDP1ALOX12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10253165-B2 | Control of organic impurities in polycarbonate synthesis | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2019-04-09 | — | — | US | claimed |
| CN-103145924-B | Insulating impregnating resin for drawing groove wedge and its curing method | HAINING YONGDA ELECTRIC MATERIAL CO LTD | 2015-05-20 | — | — | CN | claimed |
| CN-103145924-A | Insulating impregnating resin for drawing groove wedge and its curing method | HAINING YONGDA ELECTRIC NEW MATERIALS CO LTD | 2013-06-12 | — | — | CN | claimed |
| US-11945789-B2 | Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| WO-2024038035-A2 | POLYMER BRUSHES WITH CHAIN-ENDS FUNCTIONALIZED WITH METAL COORDINATING TWO HETERO ELEMENTS FOR SELECTIVE SURFACE MODIFICATION | MERCK PATENT GMBH (DE) | 2024-02-22 | — | — | WO | disclosed |
| US-20240010865-A1 | BRUSH POLYMER TERMINATED WITH PHOSPHONATE FOR DSA | MERCK PATENT GMBH (DE) | 2024-01-11 | — | — | US | disclosed |
| US-11820726-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2023-11-21 | — | — | US | disclosed |
| EP-4232486-A1 | BRUSH POLYMER TERMINATED WITH PHOSPHONATE FOR DIRECTED SELF-ASSEMBLY (DSA) | Merck Patent GmbH (DE) | 2023-08-30 | — | — | EP | disclosed |
| CN-116490527-A | Phosphonate terminated brush polymers for directed self-assembly (DSA) | 默克专利股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-115703965-A | Novel composite fluorescent material and preparation method thereof | 阜阳师范大学 | 2023-02-17 | — | — | CN | disclosed |
| US-11548846-B2 | Method of preparing 8-methyldecanal | Panasia (Wuhan) Food Science Technology Co., Ltd (CN) | 2023-01-10 | — | — | US | disclosed |
| US-20030119881-A1 | N-((2-hydroxy,3-(alkyloxo),6-halophenyl)-(1,2-cyclopropylene) -),N'-((5-cyano or bromo)pyrid-2-yl)urea; retroviricides; HIV reverse transcriptase inhibitors; prolonged time to virus resistance | MEDIVIR AB (SE) | 2003-06-26 | — | — | US | disclosed |
| WO-2003027085-A2 | 3-PYRIDYL OR 4-ISOQUINOLINYL THIAZOLES AS C17,20 LYASE INHIBITORS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| US-6486183-B1 | Antivirals | MEDIVIR AB (SE) | 2002-11-26 | — | — | US | disclosed |
| EP-1054867-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999036406-A1 | ANTIVIRALS | MEDIVIR AB (SE) | 1999-07-22 | — | — | WO | disclosed |
| US-4263290-A | DIURETICS | ROUSSEL UCLAF (FR) | 1981-04-21 | — | — | US | disclosed |
| US-4107217-A | INTERMEDIATED 3-ALKENALS | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-08-15 | — | — | US | disclosed |
| US-4088696-A | MULTISTAGE FROM AN ACETYLENIC KETONE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1978-05-09 | — | — | US | disclosed |
| US-4045497-A | Processes for producing alkenals and intermediates therefor | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1977-08-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820726-B2 | Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria | MGAM, PGLS, NISCH | ALDH1A1 4391/4885TSHR 1490/4885TDP1 3097/4885 |
| US-20030119881-A1 | N-((2-hydroxy,3-(alkyloxo),6-halophenyl)-(1,2-cyclopropylene) -),N'-((5-cyano or bromo)pyrid-2-yl)urea; retroviricides; HIV reverse transcriptase inhibitors; prolonged time to virus resistance | RAD1, POLL, PNPO | ALDH1A1 1387/4885TSHR 3128/4885TDP1 274/4885 |
| US-11945789-B2 | Inhibitors of the IRE-1/XBP-1 pathway and methods of using thereof | XBP1, DDIT3, ERN1 | ALDH1A1 2871/4885TSHR 2727/4885TDP1 1053/4885 |
| US-20240010865-A1 | BRUSH POLYMER TERMINATED WITH PHOSPHONATE FOR DSA | PHOSPHO1, MSN, HLA-DRB1 | ALDH1A1 4602/4885TSHR 4671/4885TDP1 2077/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.