Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28846015

CC(C#N)n1ccnc1-c1ccccc1.S

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.40
ESR1 P03372 1/20 0.37
KDM4E B2RXH2 1/20 0.36
CHEK1 O14757 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
LIMK1 P53667 1/20 0.36
MAPK14 Q16539 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
KMT2A Q03164 1/20 0.36
KDR P35968 7/20 0.35
ABCC9 O60706 1/20 0.34
NTRK1 P04629 1/20 0.34
PIM1 P11309 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
BACE1 P56817 1/20 0.33
FLT1 P17948 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL84081 0.98 BRD4 (0.41) BRD4ESR1KDM4ECHEK1ALDH1A1
SCHEMBL28256120 0.93 BRD4 (0.38) BRD4ESR1KDM4ECHEK1ALDH1A1
Mellitic Acid SCHEMBL28628589 0.89 ESR1 (0.41) BRD4ESR1KMT2AABCC9
2-Phenylimidazole SCHEMBL16267717 0.86 NISCH (0.51) BRD4ESR1KDM4EALDH1A1
SCHEMBL21990719 0.83 BRD4 (0.37) BRD4ESR1KDM4EALDH1A1MAPT
SCHEMBL7649337 0.82 HSD11B1 (0.41) BRD4
SCHEMBL9444404 0.81 BRD4 (0.47) BRD4ESR1KDM4ECHEK1ALDH1A1
SCHEMBL154796 0.81 KDM4E (0.39) BRD4ESR1KDM4ENTRK1RAB9A
SCHEMBL27504005 0.79 BRD4 (0.39) BRD4ESR1KDRABCC9NTRK1
SCHEMBL10364019 0.77 BRD4 (0.44) BRD4ESR1KDM4ECHEK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106947314-B A kind of printed circuit board (PCB) character marking ink composite and wiring board 深圳市容大感光科技股份有限公司 2018-03-30 CN disclosed
CN-106947314-A A kind of printed circuit board (PCB) character marking ink composite and wiring board 深圳市容大感光科技股份有限公司 2017-07-14 CN disclosed