Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3967708 | 0.88 | ACHE (0.61) | ACHEMAPTDHODHLMNAKDM4E | |
| SCHEMBL969768 | 0.81 | ACACA (0.65) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL29400688 | 0.81 | ACACA (0.65) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL28251703 | 0.81 | ACACA (0.65) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL16098115 | 0.80 | POLB (0.51) | ACP1ACHETP53MAPTGAA | |
| SCHEMBL15919363 | 0.80 | ACHE (0.77) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL13715365 | 0.80 | ACP1 (0.50) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL5795122 | 0.80 | ESRRB (0.51) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL10865746 | 0.76 | TP53 (0.48) | ACP1ACHETP53AGTR1MAPT | |
| SCHEMBL29788463 | 0.76 | DHODH (0.80) | TP53DHODHLMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106866713-A | One kind is based on 2（4 dihydroxy borines）Hypoboric acid derivative of the carboxylic acid of phenylchinoline 4 and its production and use | 山东省医学科学院药物研究所 | 2017-06-20 | — | — | CN | claimed |
| CN-106866713-A | One kind is based on 2（4 dihydroxy borines）Hypoboric acid derivative of the carboxylic acid of phenylchinoline 4 and its production and use | 山东省医学科学院药物研究所 | 2017-06-20 | — | — | CN | disclosed |