Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CALCR | P30988 | 5/20 | 0.53 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130591 | 1.00 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL30163263 | 1.00 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL14549930 | 1.00 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL28210612 | 1.00 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL30163405 | 0.99 | OPRM1 (0.56) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL30163248 | 0.99 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL29597272 | 0.98 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL14549924 | 0.97 | KEAP1 (0.56) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL11997748 | 0.97 | KEAP1 (0.56) | OPRM1OPRD1OPRK1KEAP1SLC6A2 | |
| SCHEMBL30163250 | 0.97 | KEAP1 (0.56) | OPRM1OPRD1OPRK1KEAP1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115105582-A | Pharmaceutical composition containing linaclotide or linaclotide salt and preparation method thereof | 江苏豪森药业集团有限公司 | 2022-09-27 | — | — | CN | disclosed |
| CN-105153284-B | Method for purifying linaclotide | 浙江和泽医药科技股份有限公司 | 2022-05-31 | — | — | CN | disclosed |