Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.55 |
| ▸ | CALCR | P30988 | 5/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.51 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.50 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | FCGRT | P55899 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15130591 | 0.99 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL14549930 | 0.99 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL28210612 | 0.99 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL30163263 | 0.99 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL28846618 | 0.99 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL30163405 | 0.98 | OPRM1 (0.56) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL29597272 | 0.98 | OPRM1 (0.55) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL14549924 | 0.95 | KEAP1 (0.56) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL11997748 | 0.95 | KEAP1 (0.56) | OPRM1OPRD1OPRK1KEAP1CALCR | |
| SCHEMBL30163250 | 0.95 | KEAP1 (0.56) | OPRM1OPRD1OPRK1KEAP1CALCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115575557-B | Method for detecting and analyzing linaclotide and related substances thereof | 苏州天马医药集团天吉生物制药有限公司 | 2025-02-07 | — | — | CN | claimed |
| CN-115575557-A | Detection and analysis method for linaclotide and related substances thereof | 苏州天马医药集团天吉生物制药有限公司 | 2023-01-06 | — | — | CN | claimed |
| CN-115575557-B | Method for detecting and analyzing linaclotide and related substances thereof | 苏州天马医药集团天吉生物制药有限公司 | 2025-02-07 | — | — | CN | disclosed |
| CN-116672309-A | dry suspension pharmaceutical composition | 北京普诺旺康医药科技有限公司 | 2023-09-01 | — | — | CN | disclosed |
| CN-115575557-A | Detection and analysis method for linaclotide and related substances thereof | 苏州天马医药集团天吉生物制药有限公司 | 2023-01-06 | — | — | CN | disclosed |