Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847499 | 0.82 | ALDH1A1 (0.37) | MAPTNPC1RAB9ASMN1; SMN2AAK1 | |
| SCHEMBL28847447 | 0.81 | MAPT (0.43) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28847456 | 0.81 | NPC1 (0.46) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28847474 | 0.79 | ALDH1A1 (0.36) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL28847454 | 0.77 | ALDH1A1 (0.38) | MAPTNPC1RAB9AKMT2AL3MBTL1 | |
| SCHEMBL28847427 | 0.76 | AAK1 (0.39) | MAPTRAB9ASMN1; SMN2AAK1KMT2A | |
| SCHEMBL28847416 | 0.74 | HTT (0.41) | MAPTNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL23525112 | 0.74 | ITK (0.42) | MAPTNPC1RAB9ASMN1; SMN2AAK1 | |
| SCHEMBL23525115 | 0.74 | ITK (0.42) | MAPTNPC1RAB9ASMN1; SMN2AAK1 | |
| SCHEMBL28847449 | 0.73 | MAPT (0.41) | MAPTNPC1RAB9AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |