Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28847499 | 0.85 | ALDH1A1 (0.37) | AAK1CYP3A4ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL28847473 | 0.81 | AAK1 (0.41) | AAK1CYP3A4HIF1AALDH1A1TSHR | |
| SCHEMBL28847447 | 0.74 | MAPT (0.43) | ALDH1A1SMN1; SMN2KMT2ALMNAMAPT | |
| SCHEMBL28847427 | 0.73 | AAK1 (0.39) | AAK1CYP3A4HIF1AALDH1A1TSHR | |
| SCHEMBL28847388 | 0.73 | MAPT (0.41) | AAK1ALDH1A1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL28847456 | 0.72 | NPC1 (0.46) | ALDH1A1TSHRSMN1; SMN2KMT2ALMNA | |
| SCHEMBL28847442 | 0.71 | KDM1A (0.41) | AAK1HIF1AALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL23525085 | 0.70 | AAK1 (0.48) | AAK1ALDH1A1KMT2A | |
| SCHEMBL23525084 | 0.70 | AAK1 (0.48) | AAK1ALDH1A1KMT2A | |
| SCHEMBL28847449 | 0.69 | MAPT (0.41) | CYP3A4ALDH1A1CYP2C19LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115087655-A | Benzimidazole derivatives | 辉瑞公司 | 2022-09-20 | — | — | CN | disclosed |