SCHEMBL288482

SCHEMBL288482

CC(C)(c1ccccc1)c1[c]cccc1C(C)(C)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CYP3A4 P08684 1/20 0.39
KCNN4 O15554 2/20 0.34
MAPK1 P28482 1/20 0.34
NR3C2 P08235 3/20 0.33
TAAR1 Q96RJ0 1/20 0.32
ALOX15 P16050 1/20 0.32
CRHBP P24387 1/20 0.31
CRHR2 Q13324 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
CNR1 P21554 1/20 0.30
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL984077 0.81 ESR1 (0.39) ALDH1A1ESR1ESR2CYP3A4KCNN4
SCHEMBL9787333 0.79 ESR1 (0.52) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL288010 0.78 ALDH1A1 (0.37) ALDH1A1ESR1ESR2CYP3A4KCNN4
SCHEMBL9238534 0.77 CA1 (0.40) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL984616 0.77 NR3C2 (0.38) ALDH1A1ESR1ESR2CYP3A4KCNN4
SCHEMBL2199266 0.76 ALDH1A1 (0.54) ALDH1A1ESR1ESR2CYP3A4KCNN4
SCHEMBL12817524 0.76 GABRA1 (0.33)
SCHEMBL2158943 0.76 ALDH1A1 (0.38) ALDH1A1ESR1ESR2CYP3A4MAPK1
SCHEMBL14889835 0.75 ALDH1A1 (0.33) ALDH1A1ESR1ESR2CYP3A4
SCHEMBL12816468 0.74 MAPK1 (0.32) ALDH1A1KCNN4MAPK1TAAR1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107841029-A A kind of solar cell backboard high-weatherability PE films 湖北航天化学技术研究所 2018-03-27 CN claimed
CN-103732676-A Polyolefin composition with excellent colour and thermal stability as well as oxidation resistance for pipes BOREALIS AG 2014-04-16 CN claimed
WO-2013013805-A1 POLYOLEFIN COMPOSITION WITH EXCELLENT COLOUR AND THERMAL STABILITY AS WELL AS OXIDATION RESISTANCE FOR PIPES BOREALIS AG (AT) 2013-01-31 WO claimed
EP-2551297-A1 Polyolefin composition with excellent colour and thermal stability as well as oxidation resistance for pipes Borealis AG (AT) 2013-01-30 EP claimed
CN-115627027-A Encapsulated stabilizer composition 塞特工业公司 2023-01-20 CN disclosed
US-11192853-B2 Separation method and method for producing isocyanate ASAHI KASEI CHEMICALS CORPORATION (JP) 2021-12-07 US disclosed
EP-2641896-B1 SEPARATION METHOD ASAHI CHEMICAL IND (JP) 2020-10-14 EP disclosed
US-10752753-B2 Flame-retardant compositions and related methods SMETANA, KARON Z, SMETANA, MRS. 2020-08-25 US disclosed
EP-2427049-B1 SURFACTANTS IN AGROCHEMICAL FORMULATIONS CRODA INC (US) 2020-03-18 EP disclosed
EP-2626345-B1 SEPARATION METHOD AND METHOD FOR PRODUCING ISOCYANATE ASAHI CHEMICAL IND (JP) 2019-01-16 EP disclosed
US-9950273-B2 Method of separation ASAHI KASEI CHEMICALS CORPORATION (JP) 2018-04-24 US disclosed
US-20180105489-A1 Separation Method and Method for Producing Isocyanate ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20090266991-A1 METHOD OF AUTHENTICATING TAGGED POLYMERS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-29 US disclosed
US-20090258977-A1 OPTICAL POLYMERIC COMPOSITION AND METHOD OF MAKING SAME SMETANA, KARON Z, SMETANA, MRS. 2009-10-15 US disclosed
US-20090068363-A1 POLYMERIC COMPOSITION SMETANA, KARON Z, SMETANA, MRS. 2009-03-12 US disclosed
CN-101288200-A Method of using an electrochemical cell 3M INNOVATIVE PROPERTIES CO (US) 2008-10-15 CN disclosed
EP-1749043-A1 COPOLYCARBONATES WITH AN IMPROVED FLUIDITY Bayer MaterialScience AG (DE) 2007-02-07 EP disclosed
WO-2005113639-A1 COPOLYCARBONATES WITH AN IMPROVED FLUIDITY BAYER MATERIALSCIENCE AG (DE) 2005-12-01 WO disclosed
CN-1685001-A Stabilized polymer composition BOREALIS TECH OY (FI) 2005-10-19 CN disclosed
US-6475589-B1 Colored optical discs and methods for making the same GENERAL ELECTRIC COMPANY 2002-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11192853-B2 Separation method and method for producing isocyanate IDH3A, IDH3B, CA9 ALDH1A1 278/4885ESR1 3724/4885ESR2 3969/4885
US-20180105489-A1 Separation Method and Method for Producing Isocyanate IDH3A, IDH3B, CA9 ALDH1A1 278/4885ESR1 3724/4885ESR2 3969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.