Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329703 | 0.84 | METAP2 (0.43) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL8354989 | 0.83 | METAP2 (0.42) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL4421417 | 0.83 | METAP2 (0.42) | METAP2METAP1NPY5RENPP1PTGDR2 | |
| Hydrochloric Acid SCHEMBL28848510 | 0.81 | L3MBTL1 (0.44) | METAP2METAP1NPY5RENPP1PTGDR2 | |
| SCHEMBL2556284 | 0.75 | METAP2 (0.37) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL277595 | 0.72 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1PTGDR2 | |
| SCHEMBL357003 | 0.72 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1PTGDR2 | |
| SCHEMBL2202798 | 0.71 | METAP2 (0.44) | METAP2METAP1NPY5RENPP1 | |
| Hydrochloric Acid SCHEMBL4982877 | 0.71 | METAP2 (0.46) | METAP2METAP1NPY5RENPP1PTGDR2 | |
| SCHEMBL5349501 | 0.70 | METAP2 (0.43) | METAP2METAP1NPY5RENPP1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107082782-A | Substituted xanthine and its application method | 海德拉生物科学有限公司 | 2017-08-22 | — | — | CN | disclosed |
| CN-105143229-B | Substituted xanthines and methods of use thereof | 海德拉生物科学有限公司 | 2017-06-30 | — | — | CN | disclosed |