Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4982877 | 0.98 | METAP2 (0.46) | METAP2METAP1NPY5RKDM4EHTT | |
| Purine SCHEMBL25254163 | 0.78 | KDM4E (0.59) | METAP2METAP1KDM4ERPS6KA5 | |
| SCHEMBL1963575 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL277596 | 0.75 | METAP2 (0.51) | METAP2METAP1NPY5RGRIN2BENPP1 | |
| SCHEMBL2011131 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RGRIN2BENPP1 | |
| SCHEMBL375955 | 0.75 | SMN1; SMN2 (0.52) | METAP2METAP1NPY5RHTTGRIN2B | |
| SCHEMBL3801779 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RHTTHSD17B10 | |
| SCHEMBL3894 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1 | |
| SCHEMBL5632 | 0.75 | NUDT1 (0.50) | METAP2METAP1NPY5RKDM4EHSD17B10 | |
| SCHEMBL7787137 | 0.75 | METAP2 (0.47) | METAP2METAP1NPY5RENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 600 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112245440-A | Use of tocotrienol derivatives | 北京蔚蓝之源医药科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-108484605-A | A kind of chloro- 9- of 2- amino -6-（4- acetoxy-3s-acetyl-o-methyl butyl）The preparation method of purine | 上药康丽（常州）药业有限公司 | 2018-09-04 | — | — | CN | claimed |
| EP-2663309-B1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | INFINITY PHARMACEUTICALS INC (US) | 2017-03-15 | — | — | EP | claimed |
| CN-103648499-B | Processes for preparing isoquinolinones and solid forms of isoquinolinones | 无限药品股份有限公司 | 2017-02-15 | — | — | CN | claimed |
| US-9290497-B2 | Processes for preparing isoquinolinones and solid forms of isoquinolinones | INFINITY PHARMACEUTICALS, INC. (US) | 2016-03-22 | — | — | US | claimed |
| CN-104031048-B | A kind of β-chloroethylnitrosoureas compound and preparation method and use thereof | BEIJING UNIVERSITY OF TECHNOLOGY (CN) | 2016-03-09 | — | — | CN | claimed |
| CN-105294761-A | Impurities of tenofovir disoproxil fumarate or tenofovir, and preparation method thereof | ZHEJIANG JIUZHOU PHARMACEUTICAL TECHNOLOGY CO LTD | 2016-02-03 | — | — | CN | claimed |
| US-20140371450-A1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | HCR COLLATERAL MANAGEMENT, LLC | 2014-12-18 | — | — | US | claimed |
| CN-104031048-A | Novel beta-chloroethylnitrosourea compounds, and synthesis method and application thereof | UNIV BEIJING TECHNOLOGY | 2014-09-10 | — | — | CN | claimed |
| CN-101856313-B | Association of monosaccharides and adenosine and its cosmetic use | OREAL | 2014-02-19 | — | — | CN | claimed |
| EP-1628685-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2006-03-01 | — | — | EP | claimed |
| EP-1617848-A2 | ANTI-CANCER PHOSPHONATE CONJUGATES | GILEAD SCIENCES, INC. (US) | 2006-01-25 | — | — | EP | claimed |
| WO-2005023811-A1 | PROCESS FOR THE PREPARATION OF (1S, 4R) -CIS-4-‘2-AMINO-6CHLORO-9H-PURIN-9-YL!-2-CYCLOPENTENE-1-METHANOL | GLAXO GROUP LIMITED (GB) | 2005-03-17 | — | — | WO | claimed |
| WO-2004096286-A2 | ANTIVIRAL PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| WO-2004096235-A2 | ANTI-CANCER PHOSPHONATE ANALOGS | GILEAD SCIENCES, INC. (US) | 2004-11-11 | — | — | WO | claimed |
| EP-0861841-B1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS COMPANY (JP) | 2001-04-04 | — | — | EP | claimed |
| US-5994541-A | Process for producing 2-amino-6-iodopurine | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-11-30 | — | — | US | claimed |
| CN-1226602-A | Fast culture media for mycobaterium tuberculosis and preparation thereof | LIU ZHAOYUN (CN) | 1999-08-25 | — | — | CN | claimed |
| EP-0861841-A1 | PROCESS FOR PRODUCING 2-AMINO-6-IODOPURINE | SUMIKA FINE CHEMICALS Company, Limited (JP) | 1998-09-02 | — | — | EP | claimed |
| US-3939089-A | PEROXYSULFATE | TOKAI DENKA KOGYO KABUSHIKI KAISHA (JA) | 1976-02-17 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140371450-A1 | PROCESSES FOR PREPARING ISOQUINOLINONES AND SOLID FORMS OF ISOQUINOLINONES | PIK3CA, PDPK1, AKT3 | METAP2 4567/4885METAP1 4426/4885NPY5R 4020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.