Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.43 |
| ▸ | PDE1A | P54750 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 9/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28848830 | 0.82 | PDE3B (0.43) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL946000 | 0.80 | PDE3B (0.43) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL28953804 | 0.76 | PDE3B (0.40) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL7425735 | 0.74 | PDE3B (0.52) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL944218 | 0.71 | FGFR1 (0.45) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL11073696 | 0.71 | PDE3B (0.50) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL17185938 | 0.71 | PDE3B (0.53) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL7293060 | 0.69 | PDE3B (0.54) | PDE3BPDE3APDE2APDE1APDE1B | |
| SCHEMBL20385732 | 0.69 | NOS3 (0.38) | CDC7CDK2NOS3NOS1NOS2 | |
| SCHEMBL22473990 | 0.68 | PDE3B (0.51) | PDE3BPDE3APDE2APDE1APDE1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036005-B | Amide derivatives and their use in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |