Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.30 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28835751 | 0.83 | LMNA (0.42) | LMNAALDH1A1MTNR1AMTNR1BADRB2 | |
| SCHEMBL29221508 | 0.81 | LTA4H (0.38) | LMNACA2ALDH1A1CA1LTA4H | |
| SCHEMBL27945071 | 0.78 | LTA4H (0.38) | LMNAALDH1A1TSHRLTA4H | |
| SCHEMBL20561442 | 0.77 | PCSK9 (0.37) | LMNATRPA1CA2ALDH1A1CYP3A4 | |
| SCHEMBL28115029 | 0.73 | TSHR (0.40) | LMNACYP1A2CA2ALDH1A1PTGS1 | |
| SCHEMBL4855266 | 0.71 | LMNA (0.39) | LMNATRPA1CA2ALDH1A1MTNR1A | |
| SCHEMBL4769224 | 0.71 | CA4 (0.42) | LMNACA2ALDH1A1TSHRCA1 | |
| SCHEMBL20678528 | 0.70 | LMNA (0.37) | LMNACA2ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL28126445 | 0.70 | HDAC1 (0.34) | LMNACA2ALDH1A1TSHRCA1 | |
| SCHEMBL1878004 | 0.70 | CA1 (0.46) | LMNACA2ALDH1A1MAOATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107109229-A | Device for regulating the passage of energy | 默克专利股份有限公司 | 2017-08-29 | — | — | CN | disclosed |