SCHEMBL4855266

SCHEMBL4855266

CCC(C)OB(O)Oc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
MAPT P10636 1/20 0.38
TSHR P16473 1/20 0.36
MTNR1A P48039 4/20 0.36
MTNR1B P49286 4/20 0.36
TRPA1 O75762 2/20 0.33
NPY5R Q15761 1/20 0.33
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
CYP2D6 P10635 1/20 0.33
ADRB3 P13945 1/20 0.33
MAOA P21397 1/20 0.33
PTGS1 P23219 1/20 0.33
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
LTA4H P09960 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2575659 0.81 LMNA (0.39) LMNATSHRMTNR1AMTNR1BADRB2
SCHEMBL5952719 0.74 PCSK9 (0.40) LMNAMAPTTSHRTRPA1MEN1
SCHEMBL10973345 0.73 TSHR (0.35) TSHR
SCHEMBL1878004 0.73 CA1 (0.46) LMNATSHRMAOACA1CA2
SCHEMBL2126537 0.73 LTA4H (0.41) LMNAMAPTTSHRCA1CA2
SCHEMBL28073749 0.73 CA1 (0.36) LMNATSHRCA1CA2LTA4H
SCHEMBL4851452 0.73 LMNA (0.44) LMNAMAPTTSHRMTNR1AMTNR1B
SCHEMBL28491067 0.72 LTA4H (0.39) LMNAMAPTCA1CA2LTA4H
SCHEMBL28848860 0.71 LMNA (0.36) LMNATSHRMTNR1AMTNR1BTRPA1
SCHEMBL9443206 0.71 CA1 (0.44) LMNATSHRCA1CA2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7410925-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-08-12 US disclosed
US-7008897-B2 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-03-07 US disclosed
US-20060030480-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2006-02-09 US disclosed
US-20040209763-A1 Metal compound, and catalyst component and catalyst for addition polymerization, and process for producing addition polymer SUMITOMO CHEMICAL COMPANY, LIMITED 2004-10-21 US disclosed