Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230409 | 0.73 | PRNP (0.49) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL31083578 | 0.72 | NR4A1 (0.54) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL5866499 | 0.72 | NR4A1 (0.54) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL14352993 | 0.72 | CYP2A6 (0.41) | ALDH1A1KDM4ECA1CA2HPGD | |
| SCHEMBL6233778 | 0.71 | NR4A1 (0.44) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL492059 | 0.70 | CDK9 (0.41) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL25234206 | 0.69 | NR4A1 (0.42) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL29406795 | 0.69 | NR4A1 (0.73) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL27985 | 0.69 | NR4A1 (0.73) | NR4A1NR4A2NR4A3PRNPALDH1A1 | |
| SCHEMBL11660115 | 0.68 | TBXAS1 (0.50) | NR4A1NR4A2NR4A3PRNPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074842-A | 1, 2-benzothiazole compounds for the treatment of renal disorders | 伊莱利利公司 | 2017-08-18 | — | — | CN | disclosed |