Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27966111 | 0.84 | KMT2A (0.40) | NUDT1TLR8KMT2APOLBMPO | |
| SCHEMBL22423878 | 0.77 | KMT2A (0.46) | NUDT1KMT2AMPOADORA2AADORA1 | |
| SCHEMBL28170602 | 0.76 | KMT2A (0.44) | NUDT1KMT2AMPOADORA2AADORA1 | |
| SCHEMBL28121595 | 0.75 | POLB (0.64) | NUDT1TLR8KMT2APOLBADORA2A | |
| SCHEMBL12015758 | 0.74 | NOS2 (0.59) | KMT2AHTR1BHTR2BGPR65NOS3 | |
| SCHEMBL8989811 | 0.74 | KMT2A (0.43) | TLR8KMT2APOLBHTR2CNOS3 | |
| SCHEMBL604018 | 0.74 | HRH4 (0.60) | — | |
| SCHEMBL11769375 | 0.72 | NOS2 (0.42) | KMT2AHTR1BHTR2BGPR65NOS3 | |
| SCHEMBL28505449 | 0.72 | NCF1 (0.54) | NUDT1TLR8KMT2APOLBBACE1 | |
| SCHEMBL28170660 | 0.72 | KMT2A (0.44) | NUDT1TLR8KMT2AAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107106524-A | Methods for treating protozoal infections | 尼奥酷里私人有限公司 | 2017-08-29 | — | — | CN | claimed |