SCHEMBL28849340

SCHEMBL28849340

C1=c2ccccc2=NC1Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 2/20 0.35
NOS1 P29475 5/20 0.34
NOS2 P35228 5/20 0.34
NOS3 P29474 1/20 0.34
GBA1 P04062 1/20 0.32
CTRB1 P17538 1/20 0.32
CALM1 P0DP23 1/20 0.31
MAOB P27338 1/20 0.31
FASN P49327 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29435071 0.76 NOS2 (0.30) NOS2
SCHEMBL30432831 0.72
SCHEMBL28244880 0.69 TAAR1 (0.36) TAAR1NOS1NOS2NOS3GBA1
SCHEMBL11267030 0.69 TAAR1 (0.40) TAAR1NOS1NOS2NOS3GBA1
SCHEMBL10111693 0.66
SCHEMBL27573636 0.65 TAAR1 (0.35) TAAR1NOS1NOS2NOS3GBA1
SCHEMBL28309978 0.64
Hydrochloric Acid SCHEMBL28310644 0.63
SCHEMBL10103689 0.60
SCHEMBL27601554 0.60 GBA1 (0.34) TAAR1NOS1NOS2NOS3GBA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107162951-A A kind of preparation method of the 9 oxime derivate of isatin 3 宁波大学 2017-09-15 CN disclosed
CN-107141246-A A kind of preparation method of Isatine derivatives 宁波大学 2017-09-08 CN disclosed