Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28157139 | 0.67 | TRPA1 (0.36) | GBA1TAAR1CALM1NOS1NOS2 | |
| SCHEMBL4357593 | 0.64 | CALM1 (0.45) | GBA1CALM1 | |
| SCHEMBL27576685 | 0.62 | CYP19A1 (0.62) | — | |
| SCHEMBL15946402 | 0.62 | RECQL (0.32) | TAAR1MAOB | |
| SCHEMBL4623291 | 0.61 | CALM1 (0.41) | GBA1CALM1NOS1NOS2 | |
| SCHEMBL5794073 | 0.59 | CALM1 (0.39) | GBA1CALM1NOS1NOS2 | |
| SCHEMBL6002826 | 0.59 | CALM1 (0.39) | GBA1CALM1 | |
| SCHEMBL10475464 | 0.59 | CALM1 (0.39) | GBA1TAAR1CALM1NOS1NOS2 | |
| SCHEMBL23429749 | 0.58 | — | — | |
| SCHEMBL1200483 | 0.58 | GBA1 (0.42) | GBA1CALM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1837205-A | Process for the preparation of pyrazolopyridine tartrates | PFIZER PROD INC (US) | 2006-09-27 | — | — | CN | disclosed |
| CN-1515570-A | Preparation method of pyrazolo [4, 3-c ] pyridine-3-ketone L-tartrate | �Ʒ� | 2004-07-28 | — | — | CN | disclosed |