Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.49 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849439 | 0.85 | TBXAS1 (0.76) | TBXAS1L3MBTL1TDP1LMNAMAPT | |
| SCHEMBL29950720 | 0.85 | TBXAS1 (0.76) | TBXAS1L3MBTL1TDP1LMNAMAPT | |
| SCHEMBL28454162 | 0.85 | L3MBTL1 (0.58) | TBXAS1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL4412682 | 0.82 | TBXAS1 (0.67) | TBXAS1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL28849443 | 0.80 | CYP1A2 (0.55) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL11831935 | 0.80 | NPC1 (0.56) | TBXAS1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL28618838 | 0.78 | PAM (0.53) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL25871487 | 0.78 | PAM (0.53) | HDAC1HDAC8HDAC3HDAC4HDAC7 | |
| SCHEMBL850920 | 0.75 | TBXAS1 (0.69) | TBXAS1HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL850919 | 0.75 | TBXAS1 (0.69) | TBXAS1HDAC1HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115108875-B | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by asymmetric catalysis of visible light, and preparation method and application thereof | 河南师范大学 | 2023-07-04 | — | — | CN | disclosed |
| CN-115108875-A | Nitrogen-containing heteroarene chiral cyclic alcohol constructed by visible light asymmetric catalysis, and preparation method and application thereof | 河南师范大学 | 2022-09-27 | — | — | CN | disclosed |