Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.33 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491066 | 0.78 | KDM4E (0.32) | ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL2884958 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL159595 | 0.78 | ALDH1A1 (0.39) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL721990 | 0.77 | MAOA (0.32) | ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL8682848 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10TAS1R3TAS1R1 | |
| SCHEMBL1225214 | 0.77 | NFE2L2 (0.36) | ALDH1A1KDM4EHSD17B10MAPK1SMN1; SMN2 | |
| SCHEMBL831500 | 0.77 | ALDH1A1 (0.38) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL28081292 | 0.75 | ALDH1A1 (0.32) | ALDH1A1KDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL27906216 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EHSD17B10TSHRMAPK1 | |
| SCHEMBL4085179 | 0.73 | CYP3A4 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213353-A | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2022-03-22 | — | — | CN | claimed |
| EP-2797932-A1 | METHODS OF ISOLATING (4-CHLORO-2-FLUORO-3-SUBSTITUTED-PHENYL) BORONATES AND METHODS OF USING THE SAME | Dow AgroSciences LLC (US) | 2014-11-05 | — | — | EP | claimed |
| US-8609855-B2 | Process for the preparation of 4-amino-5-fluoro-3-halo-6-(substituted)picolinates | DOW AGROSCIENCES, LLC. (US) | 2013-12-17 | — | — | US | claimed |
| WO-2013101987-A1 | METHODS OF ISOLATING (4-CHLORO-2-FLUORO-3-SUBSTITUTED-PHENYL) BORONATES AND METHODS OF USING THE SAME | DOW AGROSCIENCES LLC (US) | 2013-07-04 | — | — | WO | claimed |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA CROP PROTECTION, LLC (US) | 2012-03-01 | — | — | US | claimed |
| EP-2396306-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | Syngenta Limited (GB) | 2011-12-21 | — | — | EP | claimed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | claimed |
| CN-114213353-B | Aryl-oxazole-oxazoline compound and preparation method and application thereof | 贵州大学 | 2023-04-14 | — | — | CN | disclosed |
| US-20230083973-A1 | SUBSTITUTED CYCLOPROPYL-2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2023-03-16 | — | — | US | disclosed |
| EP-3458442-B1 | SYNTHESIS OF 6-ARYL-4-AMINOPICOLINATES AND 2-ARYL-6-AMINOPYRIMIDINE-4-CARBOXYLATES BY DIRECT SUZUKI COUPLING | CORTEVA AGRISCIENCE LLC (US) | 2022-12-28 | — | — | EP | disclosed |
| EP-4007578-A1 | SUBSTITUTED CYCLOPROPYL-2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | Arbutus Biopharma, Inc. (US) | 2022-06-08 | — | — | EP | disclosed |
| CN-114507175-A | Novel inhibitors of hypnotic proteins alpha and beta | 维沃里翁治疗股份有限公司 | 2022-05-17 | — | — | CN | disclosed |
| CN-114478506-A | Pyridine oxazole compound and application thereof | 东莞市东阳光农药研发有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-101938905-A | Chemical compounds | SYNGENTA LTD | 2011-01-05 | — | — | CN | disclosed |
| WO-2010149956-A1 | 4 -AMINOPICOLINATES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-12-29 | — | — | WO | disclosed |
| EP-2237669-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2010092339-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | SYNGENTA LIMITED (GB) | 2010-08-19 | — | — | WO | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
| US-20080153707-A1 | Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi | BASF AKITENGESELLSCHAFT (DE) | 2008-06-26 | — | — | US | disclosed |
| CN-101115723-A | Pyrazole carboxylic acid anilides, method for the production thereof and agents containing them for controlling pathogenic fungi | BASF AG (DE) | 2008-01-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153707-A1 | Pyrazolecarboxanilides, Process for Their Preparation and Compositions Comprising Them for Controlling Harmful Fungi | CBR3, C1S, PYM1 | ALDH1A1 4489/4885KDM4E 1801/4885HSD17B10 3976/4885 |
| US-20120053053-A1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS HERBICIDES | DPYD, DHODH, TYMP | ALDH1A1 1043/4885KDM4E 2202/4885HSD17B10 2183/4885 |
| US-20230083973-A1 | SUBSTITUTED CYCLOPROPYL-2,2'-BIPYRIMIDINYL COMPOUNDS, ANALOGUES THEREOF, AND METHODS USING SAME | HAVCR2, CDV3, HMBS | ALDH1A1 2781/4885KDM4E 508/4885HSD17B10 1405/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.