Nitrogen

Nitrogen

SCHEMBL28849677

COc1ccc(-c2ccc(OC)cc2)cc1.N#N

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.69
CA2 P00918 2/20 0.69
CA7 P43166 2/20 0.69
CA9 Q16790 2/20 0.69
CA12 O43570 1/20 0.69
CA14 Q9ULX7 1/20 0.69
ESR2 Q92731 1/20 0.67
NPC1 O15118 4/20 0.58
RAB9A P51151 4/20 0.58
MAPK1 P28482 2/20 0.58
TP53 P04637 2/20 0.58
CASP3 P42574 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
APP P05067 1/20 0.56
ACHE P22303 1/20 0.55
MAOB P27338 2/20 0.54
ABL1 P00519 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9151672 0.94 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL197522 0.94 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL6733562 0.94 CA1 (0.79) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL11373286 0.90 CA1 (0.85) CA1CA2CA7CA9CA12
Methyl Alcohol SCHEMBL28098026 0.88 ESR2 (0.75) CA1CA2CA7CA9CA12
Nitrogen SCHEMBL8497288 0.87 NPC1 (0.62) CA1CA2CA7CA9CA12
1,4-Dimethoxybenzene SCHEMBL11661546 0.87 CA1 (0.79) CA1CA2CA7CA9CA12
SCHEMBL920933 0.85 ABL1 (0.71) CA1CA2CA7CA9CA12
SCHEMBL7610770 0.85 LTA4H (0.67) CA1CA2CA7CA9CA12
SCHEMBL13038584 0.85 LTA4H (0.67) CA1CA2CA7CA9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105220448-B The method of material surface modifying associated with plasma and chemical method 哈尔滨工业大学 2017-08-25 CN disclosed