Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850148 | 1.00 | LMNA (0.36) | LMNAMAPTPTGER1TSHRCHRM2 | |
| SCHEMBL28850129 | 0.82 | AAK1 (0.39) | PTGER1CYP1A2SMN1; SMN2 | |
| SCHEMBL28995620 | 0.78 | SCN9A (0.38) | LMNAMAPTTSHRCHRM2CHRM4 | |
| SCHEMBL27020347 | 0.78 | ALDH1A1 (0.38) | MAPTPTGER1MET | |
| SCHEMBL23580473 | 0.76 | MTNR1A (0.37) | LMNA | |
| SCHEMBL23580474 | 0.76 | MTNR1A (0.37) | LMNA | |
| SCHEMBL28995555 | 0.74 | PLAU (0.38) | LMNAMAPTTSHRCHRM2CHRM4 | |
| SCHEMBL28995553 | 0.74 | PLAU (0.38) | LMNAMAPTTSHRCHRM2CHRM4 | |
| SCHEMBL29168974 | 0.74 | LMNA (0.36) | LMNAMAPTTSHRCHRM2CHRM4 | |
| SCHEMBL29169061 | 0.73 | LMNA (0.37) | LMNAMAPTTSHRCHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945571-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2022-08-26 | — | — | CN | disclosed |