Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10830908 | 0.85 | TDP1 (0.42) | TAAR1TDP1IDO1 | |
| SCHEMBL6359390 | 0.85 | TDP1 (0.42) | TAAR1TDP1GABRA1GABRB2 | |
| SCHEMBL27798979 | 0.85 | GABRA1 (0.36) | TAAR1GABRA1GABRB2TSHRCYP2D6 | |
| SCHEMBL4447955 | 0.79 | TAAR1 (0.41) | TAAR1TDP1GABRA1GABRB2IDO1 | |
| SCHEMBL30584986 | 0.78 | TAAR1 (0.62) | TAAR1TDP1IDO1TSHRCYP1A2 | |
| SCHEMBL216488 | 0.78 | TAAR1 (0.62) | TAAR1TDP1IDO1TSHRCYP1A2 | |
| SCHEMBL11859277 | 0.76 | TAAR1 (0.39) | TAAR1TDP1GABRA1GABRB2TSHR | |
| SCHEMBL25392754 | 0.76 | TAAR1 (0.41) | TAAR1TDP1GABRA1GABRB2IDO1 | |
| SCHEMBL10830808 | 0.76 | ALDH1A1 (0.46) | TAAR1TDP1TSHRCYP1A2 | |
| SCHEMBL28303107 | 0.76 | CA2 (0.41) | TAAR1TDP1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010530439-A | — | — | 2010-09-09 | — | — | JP | claimed |
| EP-2115059-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2009-11-11 | — | — | EP | claimed |
| WO-2008127753-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2008-10-23 | — | — | WO | claimed |
| CN-101501061-B | As the macrocylc compound of antiviral | MSD ITALIA S.R.L. (IT) | 2016-03-09 | — | — | CN | disclosed |
| EP-2115059-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008127753-A1 | FLAME RETARDANT COMPOSITION FOR USE IN STYRENICS | CHEMTURA CORPORATION (US) | 2008-10-23 | — | — | WO | disclosed |