Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MGAM | O43451 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SI | P14410 | 1/20 | 0.30 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850272 | 0.81 | NPSR1 (0.38) | NPSR1GLO1HCAR2FAAHALDH1A1 | |
| SCHEMBL28086841 | 0.81 | FAAH (0.46) | NPSR1GLO1FAAHALDH1A1MAPT | |
| SCHEMBL28470162 | 0.80 | HCAR2 (0.52) | NPSR1GLO1HCAR2ALDH1A1CYP2D6 | |
| SCHEMBL71162 | 0.77 | NPSR1 (0.41) | NPSR1GLO1HCAR2FAAHALDH1A1 | |
| SCHEMBL1405925 | 0.70 | — | — | |
| SCHEMBL1405926 | 0.70 | — | — | |
| SCHEMBL2204826 | 0.68 | ALDH1A1 (0.43) | NPSR1GLO1ALDH1A1CYP2D6SMN1; SMN2 | |
| Diethyl Maleate SCHEMBL7743777 | 0.66 | HCAR2 (0.64) | NPSR1HCAR2ALDH1A1MAPTLMNA | |
| SCHEMBL1370917 | 0.66 | — | — | |
| Diethyl Maleate SCHEMBL7743775 | 0.66 | HCAR2 (0.64) | NPSR1HCAR2ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114945566-A | Substituted tetrahydrofurans as sodium channel modulators | 沃泰克斯药物股份有限公司 | 2022-08-26 | — | — | CN | disclosed |