SCHEMBL28850335

SCHEMBL28850335

C#CC(=O)OCc1ccc(CC)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXRA P19793 1/20 0.44
RXRB P28702 1/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 1/20 0.43
THRA P10827 1/20 0.43
THRB P10828 1/20 0.43
ALDH1A1 P00352 5/20 0.42
NAAA Q02083 1/20 0.42
MAPT P10636 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
NPC1 O15118 3/20 0.41
HPGD P15428 2/20 0.41
RAB9A P51151 2/20 0.41
POLB P06746 1/20 0.39
PLK1 P53350 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A3 Q01959 1/20 0.39
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542088 0.90 KMT2A (0.45) KMT2AMEN1THRATHRBALDH1A1
SCHEMBL27912532 0.85 P2RX4 (0.47) ALDH1A1NAAAMAPTNPC1RAB9A
SCHEMBL10429091 0.82 ALDH1A1 (0.53) KMT2AALDH1A1MAPTNPC1RAB9A
SCHEMBL27930570 0.81 MMP1 (0.45) KMT2AMEN1MAPTL3MBTL1NPC1
SCHEMBL28123967 0.81 KMT2A (0.50) RXRARXRBKMT2AMEN1ALDH1A1
SCHEMBL28124409 0.81 P2RX4 (0.47) KMT2AMEN1ALDH1A1MAPTL3MBTL1
SCHEMBL28850294 0.81 CYP3A4 (0.44) RXRARXRBKMT2AMEN1THRA
SCHEMBL907611 0.81 ALDH1A1 (0.57) KMT2AALDH1A1L3MBTL1TDP1NPC1
SCHEMBL28850281 0.79 GAA (0.48) ALDH1A1MAPTL3MBTL1TDP1RAB9A
SCHEMBL1790469 0.78 ALDH1A1 (0.50) RXRARXRBKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105806-A Novel acetylenic acid ester and acetylenic amide plant antibacterial agent 西北农林科技大学 2022-03-01 CN disclosed