SCHEMBL28850281

SCHEMBL28850281

C#CC(=O)OCc1ccc(C#N)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.48
TSHR P16473 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
RAB9A P51151 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.43
SMPD1 P17405 1/20 0.43
SAE1 Q9UBE0 1/20 0.42
UBA2 Q9UBT2 1/20 0.42
HTT P42858 1/20 0.42
MAOB P27338 1/20 0.42
ALDH1A1 P00352 1/20 0.42
ABCB1 P08183 1/20 0.42
MAPT P10636 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.42
CTBP2 P56545 1/20 0.41
CYP2A6 P11509 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
CA12 O43570 1/20 0.41
CA2 P00918 1/20 0.41
CA3 P07451 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30542088 0.87 KMT2A (0.45) TSHRTDP1L3MBTL1ALDH1A1
SCHEMBL11844391 0.80 GAA (0.51) GAATSHRTDP1RAB9AL3MBTL1
SCHEMBL28850294 0.79 CYP3A4 (0.44) ALDH1A1
SCHEMBL3292009 0.79 ALDH1A1 (0.58) GAATSHRTDP1RAB9ASMPD1
SCHEMBL27930570 0.79 MMP1 (0.45) RAB9AL3MBTL1MAOBMAPT
Hydrochloric Acid SCHEMBL11844386 0.79 GAA (0.50) GAATSHRTDP1RAB9AL3MBTL1
SCHEMBL28850335 0.79 RXRA (0.44) GAATSHRTDP1RAB9AL3MBTL1
SCHEMBL114536 0.79 GAA (0.54) GAATSHRTDP1RAB9ASMPD1
SCHEMBL2659564 0.79 ALDH1A1 (0.58) GAATSHRTDP1RAB9AL3MBTL1
SCHEMBL28123967 0.79 KMT2A (0.50) TDP1L3MBTL1HTTMAOBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114105806-A Novel acetylenic acid ester and acetylenic amide plant antibacterial agent 西北农林科技大学 2022-03-01 CN disclosed