SCHEMBL28850352

SCHEMBL28850352

C=C(C)CN1C(=O)C(C)(CC(=O)O)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.48
TP53 P04637 3/20 0.44
LMNA P02545 4/20 0.44
MAPT P10636 2/20 0.44
GAA P10253 1/20 0.42
THRB P10828 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28850351 1.00 ALDH1A1 (0.48) ALDH1A1TP53LMNAMAPTGAA
SCHEMBL28850360 0.83 CNR1 (0.51) ALDH1A1TP53LMNAMAPTNPSR1
SCHEMBL28850362 0.83 CNR1 (0.51) ALDH1A1TP53LMNAMAPTNPSR1
SCHEMBL28850379 0.81 ALDH1A1 (0.69) ALDH1A1TP53MAPTGAANPSR1
SCHEMBL28850377 0.81 ALDH1A1 (0.69) ALDH1A1TP53MAPTGAANPSR1
SCHEMBL28850524 0.81 ALDH1A1 (0.45) ALDH1A1TP53LMNAMAPTGAA
SCHEMBL28850523 0.81 ALDH1A1 (0.45) ALDH1A1TP53LMNAMAPTGAA
SCHEMBL28850422 0.77 ALDH1A1 (0.52) ALDH1A1LMNAMAPTGAATHRB
SCHEMBL28850424 0.77 ALDH1A1 (0.52) ALDH1A1LMNAMAPTGAATHRB
SCHEMBL5542796 0.76 ALDH1A1 (0.49) ALDH1A1TP53LMNAMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115141135-A Preparation method of oxindole-acetic acid compound containing 3-bit chiral quaternary carbon center 四川大学 2022-10-04 CN disclosed