Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.39 |
| ▸ | HTR1A | P08908 | 14/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28086055 | 0.83 | CYP19A1 (0.46) | HTR1ACYP19A1 | |
| SCHEMBL28838816 | 0.81 | HTR7 (0.43) | HTR7HTR1ACES1 | |
| SCHEMBL20131349 | 0.77 | HTR7 (0.63) | HTR7HTR1A | |
| SCHEMBL20131348 | 0.77 | HTR7 (0.63) | HTR7HTR1A | |
| SCHEMBL28210257 | 0.75 | DAPK3 (0.41) | HTR7HTR1ACES1CYP19A1 | |
| SCHEMBL15412764 | 0.73 | CYP19A1 (0.37) | CYP19A1 | |
| SCHEMBL599314 | 0.72 | CYP19A1 (0.54) | HTR1ACYP19A1 | |
| SCHEMBL28167514 | 0.72 | CYP19A1 (0.46) | HTR1ACYP19A1 | |
| SCHEMBL27697275 | 0.72 | DYRK1A (0.35) | HTR7HTR1ACES1 | |
| SCHEMBL13448455 | 0.71 | CYP19A1 (0.41) | HTR7HTR1ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107074861-A | 9H pyrimido [4,5-B ] indoles and related analogs as BET bromodomain inhibitors | 密执安大学评议会 | 2017-08-18 | — | — | CN | disclosed |