Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 15/20 | 0.43 |
| ▸ | HTR1A | P08908 | 14/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28850451 | 0.81 | HTR7 (0.39) | HTR7HTR1ACES1 | |
| SCHEMBL8461437 | 0.73 | NR3C2 (0.44) | HTR7HTR1ACES1DRD2DRD3 | |
| SCHEMBL8941775 | 0.73 | CYP2A6 (0.47) | CES1AKR1B1 | |
| SCHEMBL8990229 | 0.72 | ACHE (0.57) | CES1AKR1B1 | |
| SCHEMBL598666 | 0.71 | CYP2A6 (0.46) | HTR7HTR1ADRD2DRD3 | |
| SCHEMBL19070853 | 0.71 | CYP2A6 (0.42) | HTR7HTR1ACES1DRD2DRD3 | |
| SCHEMBL15147099 | 0.69 | PLAU (0.56) | HTR1A | |
| SCHEMBL598142 | 0.69 | PLAU (0.56) | HTR1A | |
| SCHEMBL29978110 | 0.69 | PLAU (0.56) | HTR1A | |
| SCHEMBL23980063 | 0.69 | DRD2 (0.40) | HTR7HTR1ADRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349217-A | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2017-01-25 | — | — | CN | disclosed |