Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 4/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4B | O94953 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.31 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6136738 | 0.74 | AHR (0.48) | CYP1A2GAAMAPT | |
| SCHEMBL658301 | 0.71 | PDE3B (0.59) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL2879383 | 0.71 | CHRNB2 (0.38) | CHRNB2CHRNA4SIGMAR1GAAMAPT | |
| Bromide SCHEMBL15650437 | 0.69 | PDE3B (0.57) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL3313252 | 0.69 | CYP11B1 (0.56) | PDE3BPDE3ACHRNB2CHRNA4CYP11B1 | |
| SCHEMBL3462883 | 0.69 | CYP11B1 (0.56) | PDE3BPDE3ACYP11B1CYP11B2CYP1A2 | |
| SCHEMBL1268962 | 0.69 | HTR5A (0.42) | CYP1A2MAPTCDK5CDK5R1 | |
| SCHEMBL13806532 | 0.69 | PDE3B (0.41) | PDE3BPDE3ACHRNB2CHRNA4CYP11B1 | |
| SCHEMBL16846521 | 0.69 | BRD4 (0.59) | PDE3BPDE3ACYP11B1CYP11B2 | |
| SCHEMBL3959190 | 0.68 | PDE3B (0.40) | PDE3BPDE3ACHRNB2CHRNA4CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114980887-A | Fluoroalkyl-oxadiazoles and their use | 特纳亚治疗股份有限公司 | 2022-08-30 | — | — | CN | disclosed |