Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824163 | 0.82 | SOS1 (0.47) | NOTUMPOLQSOS1 | |
| SCHEMBL17293016 | 0.82 | SOS1 (0.47) | NOTUMPOLQSOS1 | |
| SCHEMBL2987993 | 0.80 | KMT2A (0.38) | KMT2A | |
| SCHEMBL29664135 | 0.80 | KMT2A (0.38) | KMT2A | |
| Nitrous Acid SCHEMBL28850943 | 0.79 | ASPH (0.41) | — | |
| SCHEMBL24550780 | 0.78 | KDM4E (0.49) | KMT2A | |
| SCHEMBL30536957 | 0.78 | KDM4E (0.49) | KMT2A | |
| SCHEMBL2990846 | 0.78 | ASPH (0.45) | NOTUM | |
| SCHEMBL30018797 | 0.78 | ASPH (0.45) | NOTUM | |
| SCHEMBL28883217 | 0.77 | RAB9A (0.33) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117651699-A | Compounds and compositions for the treatment of coronavirus related diseases | 诺华股份有限公司 | 2024-03-05 | — | — | CN | disclosed |
| CN-117295726-A | Heterocyclic compounds | 豪夫迈·罗氏有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-115212311-A | Pharmaceutical composition and application thereof | 苏州亚盛药业有限公司 | 2022-10-21 | — | — | CN | disclosed |
| CN-114127073-A | Imidazopyrimidines as EED inhibitors and uses thereof | 美国密歇根州立大学试剂中心 | 2022-03-01 | — | — | CN | disclosed |