Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852201 | 0.91 | APP (0.37) | APPALDH1A1 | |
| SCHEMBL28852170 | 0.82 | ATM (0.43) | ALDH1A1L3MBTL1ATMMEN1KMT2A | |
| SCHEMBL18364496 | 0.67 | FAAH (0.42) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL12294221 | 0.67 | ALDH1A1 (0.52) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL7008365 | 0.67 | ALDH1A1 (0.52) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL13021500 | 0.67 | ALDH1A1 (0.52) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL5195266 | 0.67 | ALDH1A1 (0.52) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL258462 | 0.66 | ALDH1A1 (0.62) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL168018 | 0.66 | ALDH1A1 (0.62) | APPALDH1A1L3MBTL1ATMMEN1 | |
| SCHEMBL17930277 | 0.66 | ALDH1A1 (0.62) | APPALDH1A1L3MBTL1ATMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957085-A | Synthetic method and application of polycyano-substituted indole heterocyclic compound | 华南师范大学 | 2022-08-30 | — | — | CN | disclosed |