Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28852178 | 0.82 | APP (0.41) | ATMALDH1A1KMT2AMEN1POLB | |
| SCHEMBL28852201 | 0.77 | APP (0.37) | ALDH1A1 | |
| SCHEMBL25294091 | 0.70 | SMN1; SMN2 (0.47) | ATMALDH1A1P2RX7SMN1; SMN2KMT2A | |
| SCHEMBL28862308 | 0.64 | L3MBTL1 (0.52) | ATMALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL13054009 | 0.64 | ATM (0.48) | ATMALDH1A1P2RX7SMN1; SMN2KMT2A | |
| SCHEMBL12741753 | 0.61 | TET2 (0.51) | ALDH1A1SMN1; SMN2KDM4ECYP1A2HPGD | |
| SCHEMBL140088 | 0.60 | ALDH1A1 (0.56) | ATMALDH1A1P2RX7SMN1; SMN2KMT2A | |
| SCHEMBL1127259 | 0.60 | ATM (1.00) | ATMALDH1A1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL13817620 | 0.59 | ATM (0.52) | ATMALDH1A1P2RX7SMN1; SMN2KMT2A | |
| SCHEMBL9412272 | 0.59 | ALDH1A1 (0.78) | ATMALDH1A1SMN1; SMN2KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957085-A | Synthetic method and application of polycyano-substituted indole heterocyclic compound | 华南师范大学 | 2022-08-30 | — | — | CN | disclosed |