Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645844 | 0.83 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDCISD2SMN1; SMN2 | |
| SCHEMBL12326381 | 0.75 | KDM4E (0.51) | KDM4EALDH1A1SMN1; SMN2MAPTRXFP1 | |
| SCHEMBL15733279 | 0.75 | KDM4E (0.45) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL24287368 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1GPR35 | |
| SCHEMBL28184946 | 0.74 | CYP2D6 (0.41) | KDM4EALDH1A1HPGDCISD2SMN1; SMN2 | |
| SCHEMBL15733357 | 0.74 | ADORA2A (0.46) | KDM4EALDH1A1HPGDCISD2SMN1; SMN2 | |
| SCHEMBL951068 | 0.73 | KDM4E (0.59) | KDM4EGPR35 | |
| SCHEMBL21990971 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL29669953 | 0.73 | KDM4E (0.59) | KDM4EGPR35 | |
| SCHEMBL19125812 | 0.73 | KDM4E (0.42) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103702978-B | Process for preparing 2-amino-5-cyano-N, 3-dimethylbenzamide | 拜耳知识产权有限责任公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107365263-A | Process for preparing 2-amino-5-cyano-N, 3-dimethylbenzamide | 拜耳知识产权有限责任公司 | 2017-11-21 | — | — | CN | disclosed |