Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
| ▸ | SI | P14410 | 1/20 | 0.38 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5868672 | 0.98 | LIPE (0.42) | LIPEL3MBTL1THRBATMALDH1A1 | |
| SCHEMBL21634172 | 0.90 | — | — | |
| SCHEMBL18771292 | 0.87 | GNAI3 (0.42) | LIPEL3MBTL1THRBATMALDH1A1 | |
| SCHEMBL3010245 | 0.82 | SMN1; SMN2 (0.52) | LIPEL3MBTL1THRBALDH1A1NPC1 | |
| SCHEMBL2885332 | 0.81 | GNAI3 (0.49) | LIPEALDH1A1SMN1; SMN2GAAKDM4E | |
| SCHEMBL8714621 | 0.81 | LIPE (0.57) | LIPEL3MBTL1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9651145 | 0.81 | LIPE (0.50) | LIPEL3MBTL1ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL7206184 | 0.80 | LIPE (0.47) | LIPEL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL22445170 | 0.80 | LIPE (0.44) | LIPEL3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL1383077 | 0.79 | SMN1; SMN2 (0.50) | LIPETHRBATMALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651297-B | N-benzyl-N-aryl sulfonamide derivative and preparation and application thereof | 杭州壹瑞医药科技有限公司 | 2022-05-27 | — | — | CN | disclosed |
| EP-1812149-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE, PRODUCTION PROCESS THEREOF AND TREATMENT METHOD FOR BORON-CONTAINING WATER | TORAY INDUSTRIES (JP) | 2013-06-12 | — | — | EP | disclosed |
| CN-102498095-A | Indoline derivatives | TOKYO INST TECH | 2012-06-13 | — | — | CN | disclosed |
| US-7641054-B2 | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same | TORAY INDUSTRIES, INC. (JP) | 2010-01-05 | — | — | US | disclosed |
| US-20080000843-A1 | Composite Semipermeable Membrane, Production Process Thereof, and Element, Fluid Separation Equipment and Treatment Method for Boron-Containing Water Using the Same | TORAY INDUSTRIES, INC. (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1812149-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006051888-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-18 | — | — | WO | disclosed |
| CN-1219780-C | Heterocyclic compounds binding chemotactic factor receptor | ANORMED INC (CA) | 2005-09-21 | — | — | CN | disclosed |
| EP-1494670-A1 | MEDICINE FOR TREATING CANCER | Kowa Co., Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| WO-2003086397-A1 | MEDICINE FOR TREATING CANCER | KOWA CO., LTD. (JP) | 2003-10-23 | — | — | WO | disclosed |
| CN-1351601-A | Heterocyclic compounds binding chemotactic factor receptor | ANORMED INC (CA) | 2002-05-29 | — | — | CN | disclosed |
| EP-0883613-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1998-12-16 | — | — | EP | disclosed |
| WO-1997029097-A1 | SULFONAMIDE DERIVATIVES AS 5HT7 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1997-08-14 | — | — | WO | disclosed |
| EP-0499080-A2 | Aminoacid derivatibes | MERCK PATENT GmbH (DE) | 1992-08-19 | — | — | EP | disclosed |
| EP-0481311-A2 | Aminoacid derivatives | MERCK PATENT GmbH (DE) | 1992-04-22 | — | — | EP | disclosed |
| EP-0474008-A1 | Amino acid derivatives | MERCK PATENT GmbH (DE) | 1992-03-11 | — | — | EP | disclosed |