Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.49 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.49 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18771292 | 0.91 | GNAI3 (0.42) | GNAI3GNAO1GNAI1LIPEGAA | |
| SCHEMBL11172594 | 0.89 | GNAI3 (0.40) | GNAI3GNAO1GNAI1LIPEGAA | |
| SCHEMBL21634172 | 0.86 | — | — | |
| SCHEMBL28783627 | 0.83 | GNAI3 (0.55) | GNAI3GNAO1GNAI1ALDH1A1SMN1; SMN2 | |
| SCHEMBL5868672 | 0.82 | LIPE (0.42) | LIPEGAAMGAMSIMGAM2 | |
| SCHEMBL2885378 | 0.81 | LIPE (0.44) | LIPEGAAMGAMSIMGAM2 | |
| SCHEMBL28637803 | 0.80 | GNAI3 (0.41) | GNAI3GNAO1GNAI1CHRM5CHRM3 | |
| SCHEMBL8714621 | 0.78 | LIPE (0.57) | LIPEGAAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL11817099 | 0.77 | TSHR (0.51) | LIPEGAAALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL20111517 | 0.75 | GNAI3 (0.62) | GNAI3GNAO1GNAI1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170240519-A1 | BENZOFURAN ANALOGUE AS NS4B INHIBITOR | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-08-24 | — | — | US | disclosed |
| US-20170240519-A1 | BENZOFURAN ANALOGUE AS NS4B INHIBITOR | CHANGZHOU YINSHENG PHARMACEUTICAL CO., LTD. (CN) | 2017-08-24 | — | — | US | disclosed |
| EP-3199530-A1 | BENZOFURAN ANALOGUE AS NS4B INHIBITOR | Changzhou Yinsheng Pharmaceutical Co., Ltd. (CN) | 2017-08-02 | — | — | EP | disclosed |
| EP-1869106-B1 | JANUS DENDRIMERS AND DENDRONS | DENDRITIC NANOTECHNOLOGIES INC (US) | 2014-06-25 | — | — | EP | disclosed |
| EP-1812149-B1 | SEMIPERMEABLE COMPOSITE MEMBRANE, PRODUCTION PROCESS THEREOF AND TREATMENT METHOD FOR BORON-CONTAINING WATER | TORAY INDUSTRIES (JP) | 2013-06-12 | — | — | EP | disclosed |
| US-7641054-B2 | Composite semipermeable membrane, production process thereof, and element, fluid separation equipment and treatment method for boron-containing water using the same | TORAY INDUSTRIES, INC. (JP) | 2010-01-05 | — | — | US | disclosed |
| WO-2009137380-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-12 | — | — | WO | disclosed |
| US-20090275594-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | JANSSEN PHARMACEUTICA NV (BE) | 2009-11-05 | — | — | US | disclosed |
| US-20080000843-A1 | Composite Semipermeable Membrane, Production Process Thereof, and Element, Fluid Separation Equipment and Treatment Method for Boron-Containing Water Using the Same | TORAY INDUSTRIES, INC. (JP) | 2008-01-03 | — | — | US | disclosed |
| EP-1869106-A2 | JANUS DENDRIMERS AND DENDRONS | Dendritic Nanotechnologies, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| EP-1812149-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006105043-A2 | JANUS DENDRIMERS AND DENDRONS | DENDRITIC NANOTECHNOLOGIES, INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006051888-A1 | COMPOSITE SEMIPERMEABLE MEMBRANE, PRODUCTION PROCESS THEREOF, AND ELEMENT, FLUID SEPARATION EQUIPMENT AND TREATMENT METHOD FOR BORON-CONTAINING WATER USING THE SAME | TORAY INDUSTRIES, INC. (JP) | 2006-05-18 | — | — | WO | disclosed |
| US-4430342-A | CARDIOVASCULAR DISORDERS | Hidaka, Hiroyoshi (JP) | 1984-02-07 | — | — | US | disclosed |
| US-4421754-A | ANTICOAGULANTS, MUSCLE RELAXANT | Hidaka, Hiroyoshi (JP) | 1983-12-20 | — | — | US | disclosed |
| EP-0076952-A1 | N-acyl-3-(4-(benzoylalkyl)piperazin-1-yl)-sydnonimine compound, process for production thereof, and use thereof | Hidaka, Hiroyoshi (JP) | 1983-04-20 | — | — | EP | disclosed |
| EP-0073345-A2 | Sydnonimine derivatives, process for production thereof, and use thereof | Hidaka, Hiroyoshi (JP) | 1983-03-09 | — | — | EP | disclosed |
| US-3855226-A | PROCESS OF PREPARING NOVEL PIPERAZINYLETHYL CARBAMATES | DOW CHEMICAL COMPANY, THE | 1974-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170240519-A1 | BENZOFURAN ANALOGUE AS NS4B INHIBITOR | GTF3C4, BRD4, CUL4B | GNAI3 1278/4885GNAO1 2573/4885GNAI1 848/4885 |
| US-20090275594-A1 | 3-HYDRAZONE PIPERAZINYL RIFAMYCIN DERIVATIVES USEFUL AS ANTIMICROBIAL AGENTS | RIF1, ABCC1, HDAC6 | GNAI3 2104/4885GNAO1 4328/4885GNAI1 2480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.