Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.54 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | APLNR | P35414 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10572189 | 0.87 | CALM1 (0.58) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL7684074 | 0.86 | CALM1 (0.56) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL11095464 | 0.84 | CALM1 (0.54) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL4028531 | 0.82 | CA12 (0.56) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL17225939 | 0.81 | PTGS2 (0.72) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL11123286 | 0.80 | CALM1 (0.46) | MMP8MMP12MMP13F2RL1CA12 | |
| Sulfuric Acid SCHEMBL22498734 | 0.79 | F2RL1 (0.53) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL2115708 | 0.79 | CA1 (0.62) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL31540563 | 0.79 | CA12 (0.53) | MMP8MMP12MMP13F2RL1CA12 | |
| SCHEMBL7303472 | 0.79 | CA12 (0.53) | MMP8MMP12MMP13F2RL1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107635975-A | NOVEL DGAT2 INHIBITORS | 伊莱利利公司 | 2018-01-26 | — | — | CN | disclosed |