Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | MMP12 | P39900 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11095464 | 0.98 | CALM1 (0.54) | CALM1IGF1RALOX15ALOX5CA12 | |
| SCHEMBL10572189 | 0.95 | CALM1 (0.58) | CALM1IGF1RALOX15ALOX5CA12 | |
| SCHEMBL28854259 | 0.86 | MMP8 (0.54) | CALM1ALOX5CA12CA1CA2 | |
| SCHEMBL11123286 | 0.84 | CALM1 (0.46) | CALM1IGF1RALOX15ALOX5CA12 | |
| SCHEMBL5994194 | 0.83 | PPARA (0.50) | CALM1 | |
| SCHEMBL5775963 | 0.83 | MEN1 (0.54) | CA12CA1CA2CA5ACA9 | |
| SCHEMBL21328231 | 0.83 | CA1 (0.57) | CALM1IGF1RALOX15ALOX5CA12 | |
| SCHEMBL22230546 | 0.81 | CA1 (0.55) | CALM1IGF1RALOX15ALOX5CA12 | |
| SCHEMBL28738754 | 0.81 | CA1 (0.55) | CALM1IGF1RALOX15ALOX5CA12 | |
| SCHEMBL4254058 | 0.81 | CALM1 (0.72) | CALM1IGF1RALOX15ALOX5CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482827-B1 | Matrix metalloproteinase inhibitors | PHARMACIA & UPJOHN S.P.A. (IT) | 2002-11-19 | — | — | US | disclosed |
| US-4987132-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0279681-A2 | Saturated heterocyclic carboxamide derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-24 | — | — | EP | disclosed |